Food Culture

17 Best Panera Sandwiches To Order in 2025

Published on April 14, 2025 | 0 Comments
The best Panera sandwiches include meat and vegetarian options

Interested in finding the best Panera sandwiches on the menu? While favorite foods are a highly subjective and personal topic, there are several options contending for the title of Panera Bread’s best sandwich. 

Whether you're looking for a light yet flavorful sandwich to help you reach your fitness goals or a hearty sandwich to satisfy your hunger, there is a sandwich from Panera for you. 

With a focus on clean ingredients, eco-friendly sourcing practices and handmade goodness, Panera has become a staple restaurant chain for grab-and-go food, including some of the most delicious sandwiches. 

So, let’s dive in and explore the best Panera sandwiches to find your next favorite flavor!

 

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The 17 Best Panera Bread Sandwiches

1. Smokehouse BBQ Chicken Sandwich

Savor the taste of smoky barbecue on a homemade ciabatta bun by ordering the Smokehouse BBQ Chicken Sandwich. This is one of the best Panera sandwiches for those craving a hearty meal packed with protein and flavor. 

The Smokehouse BBQ sandwich is an intensely flavorful option featuring smoked pulled chicken that’s coated in tangy barbecue sauce. This tasty Panera sandwich also has white cheddar cheese, onions and tangy garlic aioli, all served on a toasted ciabatta roll.

While it’s one of the best Panera sandwiches for taste, it may not be suitable for those searching for low-calorie fast food. This menu item has around 740 calories and 29 grams of fat, 14 of which are saturated fat.

However, it does have 45 grams of protein, making it an excellent choice for those searching for a post-workout bite. You can also get half a sandwich at many Panera stores, making it a little more balanced choice if paired with something lower in calories and fat, like a salad. 

Smokehouse BBQ Chicken is one of the best Panera sandwiches
via Panera Bread

2. Chipotle Chicken Avo Melt

The Chipotle Chicken Avocado Melt is one of the best Panera sandwiches for those looking for a fresh yet filling option. It features smoked, pulled chicken and creamy avocado paired with a zesty chipotle mayonnaise and sweet peppers, all pressed between black pepper focaccia bread. 

This is one of the best Panera sandwiches for those looking for a healthy and balanced option that’s still full of flavor. The combination of chicken, avocado and focaccia creates a great balance of protein, healthy fats and carbohydrates. The mayonnaise does add a little extra fat, including saturated fat, but you can ask for a lighter spread of mayonnaise if you just want a hint of chipotle flavor. 

While the nutritional profile is quite balanced, the calorie content of a whole sandwich may be a drawback for some. One sandwich has 920 calories, close to half the daily recommended amount for most adults. This Panera sandwich also comes with 48 grams of fat, 14 grams of which are saturated. 

On the plus side, a whole sandwich has 48 grams of protein, making picking up this Panera sandwich a top lunch food idea for those adding a high amount of protein to their diet.

A ciabatta bread sandwich with avocado, chicken and melted cheese
via Panera Bread

3. Toasted Frontega Chicken

If classic flavors are what make the best Panera sandwich for you, you’ll want to try the Toasted Frontega Chicken. It features a tasty combination of popular sandwich fillings like smoked pulled chicken and creamy mozzarella, plus basil, tomatoes and red onion on a black pepper focaccia bun. 

Effectively a chicken Caprese salad in a sandwich, this is also one of the lower-calorie options on the Panera sandwich menu. A whole sandwich has 730 calories, along with 36 grams of fat, 10 grams of which are saturated fat, and 43 grams of protein.

Along with the fat content, a major drawback for many will be the sodium content, which comes in at almost 1,900 milligrams of sodium per sandwich. With the FDA recommending a daily sodium intake of less than 2,300 milligrams, this Panera Bread sandwich takes a huge chunk out of your daily allowance. 

However, if you’re treating yourself and are searching for the best Panera sandwich based on taste alone, this is a top pick. As with other choices on this list of the best Panera sandwiches, you can also get half a sandwich to cut all the above nutritional values in half. 

A ciabatta sandwich with chicken, red onion, tomato and cheese
via Panera Bread

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4. Mediterranean Veggie

Vegetarians, rejoice! The Mediterranean Veggie is a top choice among the best Panera sandwiches for those seeking a fresh, flavorful and meat-free option. 

It features a vibrant mix of zesty peppers, cucumbers, leafy greens, red onions and vine-ripened tomatoes paired with creamy feta cheese. These delicious ingredients are then served on soft tomato basil bread that has a generous layer of hummus. 

This pick for the best vegetarian fast food sandwich is also one of the healthiest items at Panera. A whole Mediterranean Veggie Panera sandwich has only 630 calories and 14 grams of fat (4 grams of which are saturated). 

It also packs a decent protein punch with 23 grams of protein per whole sandwich and the use of lots of healthy vegetables means you’ll be getting some extra vitamins with your meal. 

Mediterranean Veggie is the best Panera sandwich for vegetarians
via Panera Bread

5. Chicken Bacon Rancher  

A bold and indulgent choice among the best Panera sandwiches the Chicken Bacon Rancher is full of flavors and high-protein ingredients.

This pick for best Panera sandwich features a flavorful combination of thick-cut bacon, pulled chicken and aged white cheddar cheese, all covered with a generous drizzle of creamy ranch dressing on a pepper focaccia. Ideal for those looking for a filling meal, this Panera sandwich has around 870 calories and 51 grams of protein.

However, a whole sandwich does have around 42 grams of total fat. With about 14 grams of this being saturated, enjoying this Panera sandwich will also put you close to your daily maximum recommended amount of saturated fat (the American Heart Association recommends consuming no more than 13 grams of saturated fat per day if following a 2,000-calorie-per-day guideline).

Yet, nobody really expects a bacon and ranch sandwich to be healthy! So, if you’re looking for an indulgent lunchtime treat, this is one of the best Panera sandwiches to turn to. 

A sandwich with chicken, bacon and ranch
via Panera Bread

6. Roasted Turkey and Avocado BLT

The Roasted Turkey and Avocado BLT is a fresh and satisfying option among the best Panera sandwiches. It features oven-roasted turkey and crispy applewood-smoked bacon perfectly paired with fresh avocado, vine-ripened tomatoes, lettuce and mayonnaise, all layered on toasted country rustic bread. 

This sandwich offers a perfect balance of traditional deli favorite flavors, making it a great choice for those who enjoy a high-quality take on the beloved BLT. With around 900 calories, 52 grams of fat and 44 grams of protein, it’s a protein-packed yet moderately indulgent option. 

If it sounds appealing but the calorie and fat content are a little high for you, this is one of the best Panera sandwiches to order in a half portion and pair it with soup or a salad. You can also get chicken instead of turkey, but this is really only a taste preference change, as the nutritional profile is not altered much with the switch. 

A sandwich with turkey, bacon, avocado, lettuce and tomato
via Panera Bread

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7. Toasted Garden Caprese Melt

As the name suggests, the Toasted Garden Caprese Melt is a fresh and flavorful vegetarian option among the best Panera sandwiches, taking the classic flavors of a Caprese salad and pairing them between delicious, toasty bread.

Unsurprisingly, the Toasted Garden Caprese Melt features melty mozzarella, fresh basil and tomato, plus arugula and a balsamic vinaigrette, all sandwiched between toasted ciabatta bread.  

While this is one of Panera Bread's best sandwiches for vegetarians, it isn’t the healthiest option. This Panera sandwich has around 900 calories and 48 grams of fat, 16 grams of which are saturated fat.

It also has about 55% of your daily sodium at 1,280 milligrams per whole sandwich. However, a Toasted Garden Caprese Melt does have 32 grams of protein, making it a go-to meal for vegetarians looking for a protein-heavy lunch.  

The Toasted Garden Caprese Melt is one of the best Panera sandwiches for classic flavors
via Panera Bread

8. Ciabatta Cheesesteak 

Featuring tender marinated sliced steak, provolone cheese, caramelized onions, peppers and creamy garlic aioli on a toasted artisan ciabatta, the Ciabatta Cheesesteak is a bold and savory option in the running for the title of Panera Bread’s best sandwich.

This fresh twist on the classic Philly cheesesteak is definitely a treat option, though. One sandwich has around 1,040 calories, 52 grams of fat and 1,860 milligrams of sodium, which packs a punch at approximately 80% of your daily allowance.

Thanks to the steak, it does have 52 grams of protein, making this another of the best Panera sandwiches for those looking for a substantial and protein-heavy sandwich instead of a low-calorie lunch.  

A ciabatta cheesesteak sandwich
via Panera Bread

9. Cranberry-Walnut Chicken Salad Sandwich

This limited-time treat is well worth picking up when it appears on the Panera Bread sandwich menu. A unique twist on a classic chicken salad sandwich, this pick for best Panera sandwich features tender, diced chicken tossed in a light, flavorful dressing with the addition of cranberries and healthy nuts (walnuts, specifically).

Served on country rustic sourdough bread with fresh greens and tomato, this sandwich is both satisfying, refreshing and served on one of Panera’s healthiest bread options. It has about 700 calories, 30 grams of fat and 39 grams of protein, making it a filling yet balanced meal.  

A sandwich with chicken salad, cranberries and walnuts
via Panera Bread

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10. Grilled Cheese 

The Grilled Cheese is a staple sandwich and one of the best Panera sandwiches for cheese lovers. This classic option features American cheese between two slices of white bread. It’s also toasted together for a gooey and delicious treat. 

This pick always ranks high on lists of the best Panera sandwiches because it provides a rich, creamy and indulgent flavor that appeals to those who enjoy classic comfort food. However, it’s another Panera sandwich that won’t agree with a healthy diet. 

The sandwich has 880 calories, 2,370 milligrams of sodium (exceeding an adult’s average daily allowance) and 51 grams of fat, 31 grams of which are saturated. It also features American cheese, which most should know isn’t one of the healthiest cheeses.

The sandwich does have 37 grams of protein, but if you’re looking for a protein-rich sandwich, you can find healthier options on this list of the best Panera sandwiches. 

Ultimately, this is a treat food and one that pairs perfectly with Panera’s tomato soup. If you want to simply quell a craving, you can get a Kid's Grilled Cheese with white or whole wheat bread, which has 290 or 230 calories, respectively, plus around 9 grams of fat. 

A grilled cheese sandwich with American cheese
via Panera Bread

11. Spicy Fiesta Chicken 

Bold and flavorful, the Spicy Fiesta Chicken is one of the best Panera sandwiches for diners who enjoy a spicy kick. This Southwest-inspired sandwich features grilled chicken, creamy salsa verde and aged white cheddar, plus vegetables like sweet peppers and roasted corn on a ciabatta bun. 

This tasty sandwich combines a satisfying mix of heat, creaminess and crunch and has about 840 calories, 32 grams of fat (14 grams of which are saturated fat) and 52 grams of protein.

While some of these values are a little high, such as the 14 grams of saturated fat being at or close to the recommended daily allowance, it’s one of the healthier options on this list of the best Panera sandwiches. The high amount of lean protein will also be appealing to many. 

Spicy Fiesta Chicken is one of the best Panera sandwiches for flavor and protein
via Panera Bread

12. Bacon Turkey Bravo Sandwich

Combining a range of popular fillings, the Bacon Turkey Bravo is one of the most highly-rated Panera sandwiches. It is made with oven-roasted turkey, crispy bacon and aged cheddar, plus fresh tomato and lettuce, all drizzled with signature sauce and served on a deliciously soft tomato basil bread.

This is the best Panera sandwich for those who want a twist on a classic BLT, thanks to the addition of turkey, cheese and a flavorful tomato bread. While seeming a little healthier than the toasted Panera sandwiches, a full Bacon Turkey Bravo still comes in at 1,000 calories.

A whole sandwich also has 41 grams of total fat, 15 grams of saturated fat and 54 grams of protein. To reduce fat and calories a little, you could forgo the bacon or cheese. However, doing so will also drop the protein content of the sandwich. 

A tomato bread sandwich with turkey, cheese and salad
via Panera Bread

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13. Chicken Roma Asiago Bagel Stack 

The Chicken Roma Asiago Bagel Stack is a limited-time offering. But, despite only being around for a brief time, it’s already won the title of being one of the best Panera sandwiches. 

This hearty sandwich is a versatile option that you can grab from the Panera breakfast menu for a filling start to the day or enjoy it for lunch. It’s made with grilled chicken, fresh mozzarella, tomatoes, basil and arugula. These are then all drizzled with Green Goddess dressing and sandwiched in an Asiago bagel.

Despite featuring mozzarella and Asiago cheese, this is one of the lower-calorie Panera sandwiches. A whole Chicken Roma Asiago Bagel has 580 calories, plus 24 grams of total fat, 8 grams of saturated fat and 32 grams of protein.

An Asiago bagel filled with chicken, cheese, lettuce and tomato
via Panera Bread

14. Tuna Salad Sandwich 

The Tuna Salad Sandwich is a classic and refreshing option, landing it among the best Panera sandwiches. This summertime favorite features a generous portion of tuna salad made with flaky tuna, mayonnaise, a hint of celery and seasoning, all served on fresh sourdough bread with leafy greens and ripe tomatoes. 

This contender for the best Panera sandwich is also quite healthy. A whole sandwich has around 550 calories, 28 grams of fat and 24 grams of protein. This sandwich is great for those craving a lighter lunch with plenty of protein. Sodium does come in at around 40% of your daily allowance, but if sodium is limited in other meals, this sandwich is a healthy and filling choice. 

A tuna salad sandwich is one of the best Panera sandwiches for pescatarians
via Panera Bread

15. Spicy Steak Asiago Bagel Stack 

If an Asiago bagel sandwich sounds good to you, but you want a meat with a little more protein than chicken, you’ll want to check out the Spicy Steak Asiago Bagel Stack. Indulge in tender marinated steak and provolone, paired with salsa verde, fresh arugula, red onions and sweet peppers.

A whole bagel sandwich has 590 calories, 23 grams of total fat, 11 grams of saturated fat and 39 grams of protein, making it a relatively healthy meal that fits into your daily macros. It’s also one of the best Panera sandwiches for those looking for a low-calorie, high-protein option. 

An Asiago bagel filled with steak, cheese and salad
via Panera Bread

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16. Turkey and Cheddar Sandwich 

​​If you enjoy a classic turkey sandwich, then the Turkey and Cheddar Sandwich is one of the best Panera sandwiches for you. Savor a fresh and light option with slices of tender, oven-roasted turkey, white cheddar, lettuce, tomato and mayonnaise, all served on freshly baked bread of your choice. 

This simple sandwich delivers a classic flavor combination with a healthy mix of lean protein and vegetables. Clocking in at around 780 calories with 45 grams of fat and 41 grams of protein, this sandwich may not be considered the healthiest sandwich at Panera Bread, but it still makes a satisfying meal with a good amount of protein to fuel you for the day. 

A sandwich with cheese, sliced turkey and salad
via Panera Bread

17. Toasted Italiano

Featuring popular deli fillings between delicious, freshly baked baguette, the Toasted Italiano is one of the best Panera sandwiches for those after a refined take on a classic sub. Fillings include sopressata, Black Forest ham and melty provolone. 

You’ll also get added crunch and flavor from sliced pepperoncini peppers, red onions and crisp lettuce. It’s finished with a drizzle of Greek dressing and garlic aioli for a lunchtime treat that will make you feel like you’re on vacation. 

However, this delicious sandwich at Panera does come with quite a calorie hit at 1,250 calories for a whole sandwich. A whole Toasted Italiano also has 61 grams of fat, 18 of which are saturated fat, and a whopping 3,360 milligrams of sodium.

Although a whole sandwich does offer 59 grams of protein, this will be a once-in-a-while treat option for most. Taking the half a sandwich option is also a good idea with this pick. If you have to watch your sodium intake, it’s probably best to avoid this one altogether. 

A baguette with deli meat, melted cheese and salad
via Panera Bread

What Is the Best Panera Sandwich?

The best Panera sandwiches can vary depending on personal preferences and dietary needs. One of the most popular choices is the hearty Smokehouse BBQ Chicken Sandwich, thanks to its savory combination of smoked chicken, onions and barbecue sauce. 

Another highly-rated option is the Toasted Frontega Chicken, which offers a flavorful mix of smoky pulled chicken, mozzarella and chipotle mayonnaise. These sandwiches are notably favorites for those who crave a hearty, indulgent meal with bold flavors.

For a high-protein choice, try the Spicy Fiesta Chicken, which is bursting with flavor and packed with lean protein, plus indulgent cheese and spicy peppers.

If you're looking for a low-calorie lunch option at one of the healthiest fast food chains, the Mediterranean Veggie Sandwich is the best sandwich at Panera for you. It offers a fresh combination of veggies, hummus and feta, making it perfect for vegetarians or anyone seeking a healthy meal. 

With the option to get half a sandwich, you can also enjoy any item on this list of the best Panera sandwiches while not going over calorie, fat or sodium allowances for the day. This option also gives you the choice to mix and match sandwiches if you can’t decide on a sole pick for the best Panera sandwich.

The best Panera sandwich depends on your taste preferences and health goals
via Panera Bread

The best Panera sandwiches truly depend on your personal preferences and dietary goals. Conveniently, Panera Bread offers a diverse selection to cater to a wide range of taste preferences and dietary needs. With options that cover everything from bold and indulgent to fresh and light, there's a sandwich at Panera for every craving. 

For even more ways to explore your favorite foods, check out other experiences happening on Cozymeal.